HIV
MUTATION
BROWSER
structure
P04608
False
   
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Sequence
Feature
Table
         
gene:
gag
gag-pol
env
tat
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rev
vif
vpr
vpu
         
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offset
?
HV1H2 sequence
Number of mutations for residue
?
chain
?
domain
?
short sequence motif
?
ELM
?
site of interest
?
modified residue
?
cross-link
?
region of interest
?
secondary structure ( + details )
?
PDB
?
splice variant
?
Intrinsic disorder score
?
 
|1
|51
|86
M
E
P
V
D
P
R
L
E
P
W
K
H
P
G
S
Q
P
K
T
A
C
T
N
C
Y
C
K
K
C
C
F
H
C
Q
V
C
F
I
T
K
A
L
G
I
S
Y
G
R
K
K
R
R
Q
R
R
R
A
H
Q
N
S
Q
T
H
Q
A
S
L
S
K
Q
P
T
S
Q
P
R
G
D
P
T
G
P
K
E
2
7
3
2
3
2
4
2
2
5
3
3
2
1
1
2
4
1
4
4
7
3
3
3
3
4
6
1
4
3
2
2
9
2
3
4
8
4
8
2
1
1
2
2
5
1
5
6
4
5
6
5
4
4
4
4
1
2
2
4
4
1
1
1
1
1
2
6
1
2
1
3
1
2
3
Protein Tat
Tat (7.6e-30)
Nuclear localization signal, RNA-binding (TAR), and protein transduction
Cell attachment site
NLS_MonoCore
Essential for Tat's translocation through the endosomal membrane
 
 
 
 
 
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
Transactivation
Interaction with the host capping enzyme RNGTT
Interaction with human CREBBP
Core
Cysteine-rich
3MI9
3MIA
In isoform Short.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Click on orange bars in mutation barplot or residue in sequence for detailed mutagenesis information for a residue. All data is mapped to the HXB2 isolate.