structure
P04608 False
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offset
HV1H2 sequence
Number of mutations for residue
chain
domain
short sequence motif
ELM
site of interest
modified residue
region of interest
secondary structure ( + details )
PDB
splice variant
Intrinsic disorder score
 
|1
|51
|86
M
E
P
V
D
P
R
L
E
P
W
K
H
P
G
S
Q
P
K
T
A
C
T
N
C
Y
C
K
K
C
C
F
H
C
Q
V
C
F
I
T
K
A
L
G
I
S
Y
G
R
K
K
R
R
Q
R
R
R
A
H
Q
N
S
Q
T
H
Q
A
S
L
S
K
Q
P
T
S
Q
P
R
G
D
P
T
G
P
K
E
Protein Tat
Nuclear localization signal, RNA-binding (TAR), and protein transduction
Cell attachment site
Essential for Tat's translocation through the endosomal membrane
 
 
 
 
 
Transactivation
Interaction with the host capping enzyme RNGTT
Interaction with human CREBBP
Core
Cysteine-rich
In isoform Short.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Click on orange bars in mutation barplot or residue in sequence for detailed mutagenesis information for a residue. All data is mapped to the HXB2 isolate.
Citation : Davey NE*, Satagopam VP*, Santiago-Mozos S*, Villacorta-Martin C, Bharat TA, Schneider R, Briggs JA.
The HIV Mutation Browser: A Resource for Human Immunodeficiency Virus Mutagenesis and Polymorphism Data.
PLoS Comput Biol. 2014 Dec 4;10(12):e1003951. [PubMed | PLoS ]

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