structure
P69723 False
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offset
HV1H2 sequence
Number of mutations for residue
chain
domain
short sequence motif
site of interest
modified residue
region of interest
Intrinsic disorder score
?
 
|1
|51
|101
|151
|192
M
E
N
R
W
Q
V
M
I
V
W
Q
V
D
R
M
R
I
R
T
W
K
S
L
V
K
H
H
M
Y
V
S
G
K
A
R
G
W
F
Y
R
H
H
Y
E
S
P
H
P
R
I
S
S
E
V
H
I
P
L
G
D
A
R
L
V
I
T
T
Y
W
G
L
H
T
G
E
R
D
W
H
L
G
Q
G
V
S
I
E
W
R
K
K
R
Y
S
T
Q
V
D
P
E
L
A
D
Q
L
I
H
L
Y
Y
F
D
C
F
S
D
S
A
I
R
K
A
L
L
G
H
I
V
S
P
R
C
E
Y
Q
A
G
H
N
K
V
G
S
L
Q
Y
L
A
L
A
A
L
I
T
P
K
K
I
K
P
P
L
P
S
V
T
K
L
T
E
D
R
W
N
K
P
Q
K
T
K
G
H
R
G
S
H
T
M
N
G
H
Virion infectivity factor
p17
p7
HCCH motif
BC-box-like motif
Cleavage in virion (by viral protease)
 
 
 
 
 
Interaction with host APOBEC3F; F1-box
Interaction with host APOBEC3G; G-box
Interaction with host APOBEC3F and APOBEC3G; FG-box
Interaction with host APOBEC3F; F2-box
Multimerization
Membrane association
RNA-binding
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Click on orange bars in mutation barplot or residue in sequence for detailed mutagenesis information for a residue. All data is mapped to the HXB2 isolate.
Citation : Davey NE*, Satagopam VP*, Santiago-Mozos S*, Villacorta-Martin C, Bharat TA, Schneider R, Briggs JA.
The HIV Mutation Browser: A Resource for Human Immunodeficiency Virus Mutagenesis and Polymorphism Data.
PLoS Comput Biol. 2014 Dec 4;10(12):e1003951. [PubMed | PLoS ]

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